※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (8) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tub-0057	ENSTBEG00000002304.1
2		iEKPD-Tub-0132	ENSTBEG00000005909.1
3		iEKPD-Tub-0148	ENSTBEG00000006556.1
4		iEKPD-Tub-0311	ENSTBEG00000013964.1
5		iEKPD-Tub-0317	ENSTBEG00000014083.1
6		iEKPD-Tub-0334	ENSTBEG00000014770.1
7		iEKPD-Tub-0359	ENSTBEG00000015972.1
8		iEKPD-Tub-0397	ENSTBEG00000017583.1