Xiphophorus maculatus      AGC/RSK


※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylates ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Xim-0003
ENSXMAG00000000125.1
M3ZD50
2
iEKPD-Xim-0151
ENSXMAG00000004706.1
M3ZRA4
3
iEKPD-Xim-0168
ENSXMAG00000005217.1
M3ZST8
4
iEKPD-Xim-0311
ENSXMAG00000010135.1
M4A6Z3
5
iEKPD-Xim-0365
ENSXMAG00000011838.1
M4ABS3
6
iEKPD-Xim-0488
ENSXMAG00000015712.1
M4AMS0
7
iEKPD-Xim-0535
ENSXMAG00000016985.1
M4ARD9
8
iEKPD-Xim-0588
ENSXMAG00000018844.1
M4AWW5