Bos taurus      Asp-Based PTP/EYA


※ EYA family introduction

    Eyes absent protein phosphatase (EYA) belongs to a family of phosphatase which uses an Asp nucleophile for catalysis. Eye protein is characterized by its highly conserved C-terminal domain Eye domain(ED) ~270 amino acids, which also contains a phosphatase catalytic domain. Mammals EYA family contains four members, known as, EYA1-4 and Drosophila has only one gene (1).

Reference
1. Jemc, J. and Rebay, I. (2007) The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. Annu Rev Biochem, 76, 513-538. PMID: 17341163


There are 4 genes.  Reviewed (1 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Bot-0513
ENSBTAG00000013336.3
Q58DB6
EYA2
2
iEKPD-Bot-0528
ENSBTAG00000011298.5
F1MKX9
EYA1
3
iEKPD-Bot-0519
ENSBTAG00000043989.2
F1MGK4
EYA3
4
iEKPD-Bot-0529
ENSBTAG00000021970.5
E1BD15
EYA4