Fukomys damarensis      Asp-Based PTP/EYA


※ EYA family introduction

    Eyes absent protein phosphatase (EYA) belongs to a family of phosphatase which uses an Asp nucleophile for catalysis. Eye protein is characterized by its highly conserved C-terminal domain Eye domain(ED) ~270 amino acids, which also contains a phosphatase catalytic domain. Mammals EYA family contains four members, known as, EYA1-4 and Drosophila has only one gene (1).

Reference
1. Jemc, J. and Rebay, I. (2007) The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. Annu Rev Biochem, 76, 513-538. PMID: 17341163


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Fud-0541
ENSFDAG00000009297.1
2
iEKPD-Fud-0560
ENSFDAG00000011290.1
A0A091EPQ3
H920_00838
3
iEKPD-Fud-0552
ENSFDAG00000010757.1
A0A091DMH9
H920_06380
4
iEKPD-Fud-0510
ENSFDAG00000006268.1
A0A091CUS0
H920_17183