Ictidomys tridecemlineatus      Asp-Based PTP/EYA


※ EYA family introduction

    Eyes absent protein phosphatase (EYA) belongs to a family of phosphatase which uses an Asp nucleophile for catalysis. Eye protein is characterized by its highly conserved C-terminal domain Eye domain(ED) ~270 amino acids, which also contains a phosphatase catalytic domain. Mammals EYA family contains four members, known as, EYA1-4 and Drosophila has only one gene (1).

Reference
1. Jemc, J. and Rebay, I. (2007) The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. Annu Rev Biochem, 76, 513-538. PMID: 17341163


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ict-0541
ENSSTOG00000005218.3
I3M5P9
EYA1
2
iEKPD-Ict-0533
ENSSTOG00000004846.3
I3M4Z5
EYA2
3
iEKPD-Ict-0478
ENSSTOG00000004478.3
A0A287DAL4
EYA3
4
iEKPD-Ict-0538
ENSSTOG00000005069.3
A0A287CX87
EYA4