Macaca fascicularis      Asp-Based PTP/EYA


※ EYA family introduction

    Eyes absent protein phosphatase (EYA) belongs to a family of phosphatase which uses an Asp nucleophile for catalysis. Eye protein is characterized by its highly conserved C-terminal domain Eye domain(ED) ~270 amino acids, which also contains a phosphatase catalytic domain. Mammals EYA family contains four members, known as, EYA1-4 and Drosophila has only one gene (1).

Reference
1. Jemc, J. and Rebay, I. (2007) The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. Annu Rev Biochem, 76, 513-538. PMID: 17341163


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Maf-0605
ENSMFAG00000039522.1
G7PG29
EGM_02001
2
iEKPD-Maf-0591
ENSMFAG00000037522.1
G7P345
EGM_14002
3
iEKPD-Maf-0539
ENSMFAG00000030151.1
G7PC08
EYA1
4
iEKPD-Maf-0640
ENSMFAG00000045224.1
G7NWV3
EYA3