Mus musculus      Asp-Based PTP/EYA


※ EYA family introduction

    Eyes absent protein phosphatase (EYA) belongs to a family of phosphatase which uses an Asp nucleophile for catalysis. Eye protein is characterized by its highly conserved C-terminal domain Eye domain(ED) ~270 amino acids, which also contains a phosphatase catalytic domain. Mammals EYA family contains four members, known as, EYA1-4 and Drosophila has only one gene (1).

Reference
1. Jemc, J. and Rebay, I. (2007) The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. Annu Rev Biochem, 76, 513-538. PMID: 17341163


There are 4 genes.  Reviewed (4 or Unreviewed (0

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Mum-0529
ENSMUSG00000025932.14
P97767
Eya1
2
iEKPD-Mum-0531
ENSMUSG00000017897.18
O08575
Eya2
3
iEKPD-Mum-0520
ENSMUSG00000028886.15
P97480
Eya3
4
iEKPD-Mum-0535
ENSMUSG00000010461.15
Q9Z191
Eya4