Oryzias latipes      Asp-Based PTP/EYA


※ EYA family introduction

    Eyes absent protein phosphatase (EYA) belongs to a family of phosphatase which uses an Asp nucleophile for catalysis. Eye protein is characterized by its highly conserved C-terminal domain Eye domain(ED) ~270 amino acids, which also contains a phosphatase catalytic domain. Mammals EYA family contains four members, known as, EYA1-4 and Drosophila has only one gene (1).

Reference
1. Jemc, J. and Rebay, I. (2007) The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. Annu Rev Biochem, 76, 513-538. PMID: 17341163


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ore-0623
ENSORLG00000008056.1
H2LVH1
eya1
2
iEKPD-Ore-0630
ENSORLG00000006206.1
H2LP22
eya2
3
iEKPD-Ore-0619
ENSORLG00000009396.1
H2M055
eya3
4
iEKPD-Ore-0627
ENSORLG00000016484.1
H2MPH8
eya4