Physcomitrella patens      Asp-Based PTP/EYA


※ EYA family introduction

    Eyes absent protein phosphatase (EYA) belongs to a family of phosphatase which uses an Asp nucleophile for catalysis. Eye protein is characterized by its highly conserved C-terminal domain Eye domain(ED) ~270 amino acids, which also contains a phosphatase catalytic domain. Mammals EYA family contains four members, known as, EYA1-4 and Drosophila has only one gene (1).

Reference
1. Jemc, J. and Rebay, I. (2007) The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. Annu Rev Biochem, 76, 513-538. PMID: 17341163


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Php-0819
PP1S173_70V6
2
iEKPD-Php-0846
PP1S30_306V6
A9RV98
PHYPADRAFT_119866
3
iEKPD-Php-0850
PP1S84_248V6
A9SJE7
PHYPADRAFT_130776
4
iEKPD-Php-0843
PP1S171_5V6
A9T5Z8
PHYPADRAFT_140836