Sarcophilus harrisii      Asp-Based PTP/EYA


※ EYA family introduction

    Eyes absent protein phosphatase (EYA) belongs to a family of phosphatase which uses an Asp nucleophile for catalysis. Eye protein is characterized by its highly conserved C-terminal domain Eye domain(ED) ~270 amino acids, which also contains a phosphatase catalytic domain. Mammals EYA family contains four members, known as, EYA1-4 and Drosophila has only one gene (1).

Reference
1. Jemc, J. and Rebay, I. (2007) The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. Annu Rev Biochem, 76, 513-538. PMID: 17341163


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Sah-0492
ENSSHAG00000010078.1
G3W8I1
EYA1
2
iEKPD-Sah-0478
ENSSHAG00000016932.1
G3WX01
EYA2
3
iEKPD-Sah-0493
ENSSHAG00000015428.1
G3WRW5
EYA3
4
iEKPD-Sah-0491
ENSSHAG00000012982.1
G3WIH1
EYA4