Tetraodon nigroviridis      Asp-Based PTP/EYA


※ EYA family introduction

    Eyes absent protein phosphatase (EYA) belongs to a family of phosphatase which uses an Asp nucleophile for catalysis. Eye protein is characterized by its highly conserved C-terminal domain Eye domain(ED) ~270 amino acids, which also contains a phosphatase catalytic domain. Mammals EYA family contains four members, known as, EYA1-4 and Drosophila has only one gene (1).

Reference
1. Jemc, J. and Rebay, I. (2007) The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. Annu Rev Biochem, 76, 513-538. PMID: 17341163


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ten-0694
ENSTNIG00000000209.1
H3BZX3
2
iEKPD-Ten-0675
ENSTNIG00000007070.1
H3CNN8
3
iEKPD-Ten-0669
ENSTNIG00000008189.1
H3CRY1
4
iEKPD-Ten-0682
ENSTNIG00000008190.1
H3C5Y9
5
iEKPD-Ten-0644
ENSTNIG00000016327.1
H3DFX7