Anas platyrhynchos      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Anp-0260
ENSAPLG00000010615.1
U3ISW2
2
iEKPD-Anp-0409
ENSAPLG00000016110.1
R0K6S7
ADCK1
3
iEKPD-Anp-0404
ENSAPLG00000015876.1
U3J8C7
ADCK2
4
iEKPD-Anp-0368
ENSAPLG00000014501.1
U3J4H9
COQ8A