Cavia porcellus      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cap-0247
ENSCPOG00000010653.4
H0VHD6
ADCK1
2
iEKPD-Cap-0437
ENSCPOG00000031703.1
A0A286X8N0
ADCK2
3
iEKPD-Cap-0262
ENSCPOG00000011442.4
H0VJ67
ADCK5
4
iEKPD-Cap-0263
ENSCPOG00000011445.4
A0A286XRR2
COQ8A
5
iEKPD-Cap-0317
ENSCPOG00000013663.4
H0VP88
COQ8B