※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074

  Reviewed (0)  or Unreviewed (16) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Chr-0097	CHLREDRAFT_120332	A8J7T9	AKC1
2		iEKPD-Chr-0520	CHLREDRAFT_205779	A8IMV6	AKC2
3		iEKPD-Chr-0518	CHLREDRAFT_205743	A8J9R1	AKC3
4		iEKPD-Chr-0052	CHLREDRAFT_113685	A8HSC5	AKC4
5		iEKPD-Chr-0012	CHLREDRAFT_101909	A8HQL6	CHLREDRAFT_101909
6		iEKPD-Chr-0025	CHLREDRAFT_104846	A8J467	CHLREDRAFT_104846
7		iEKPD-Chr-0027	CHLREDRAFT_104934	A8J7G3	CHLREDRAFT_104934
8		iEKPD-Chr-0039	CHLREDRAFT_111503	A8IBU9	CHLREDRAFT_111503
9		iEKPD-Chr-0053	CHLREDRAFT_113847	A8HTY7	CHLREDRAFT_113847
10		iEKPD-Chr-0111	CHLREDRAFT_123240	A8JH17	CHLREDRAFT_123240
11		iEKPD-Chr-0280	CHLREDRAFT_165812	A8IBE0	CHLREDRAFT_165812
12		iEKPD-Chr-0312	CHLREDRAFT_171281	A8IU04	CHLREDRAFT_171281
13		iEKPD-Chr-0355	CHLREDRAFT_175127	A8J2P5	CHLREDRAFT_175127
14		iEKPD-Chr-0423	CHLREDRAFT_187069	A8HW69	CHLREDRAFT_187069
15		iEKPD-Chr-0115	CHLREDRAFT_126076	A8IBJ5	COQ8
16		iEKPD-Chr-0519	CHLREDRAFT_205767	A8I453	EYE3