Cyanidioschyzon merolae      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cym-0001
CMA056C
M1VE54
CYME_CMA056C
2
iEKPD-Cym-0003
CMB043C
M1V6F0
CYME_CMB043C
3
iEKPD-Cym-0015
CMG075C
M1UQ21
CYME_CMG075C
4
iEKPD-Cym-0017
CMG161C
M1VG94
CYME_CMG161C
5
iEKPD-Cym-0025
CML057C
M1V5H5
CYME_CML057C
6
iEKPD-Cym-0033
CMN159C
M1V5U1
CYME_CMN159C
7
iEKPD-Cym-0043
CMP122C
M1V9V6
CYME_CMP122C
8
iEKPD-Cym-0052
CMQ260C
M1UVS6
CYME_CMQ260C
9
iEKPD-Cym-0060
CMR400C
M1UWH9
CYME_CMR400C
10
iEKPD-Cym-0062
CMS164C
M1VBP8
CYME_CMS164C
11
iEKPD-Cym-0069
CMT177C
M1UXH2
CYME_CMT177C