Danio rerio      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 6 genes.  Reviewed (2 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dar-0158
ENSDARG00000020123.10
Q5RGU1
coq8a
2
iEKPD-Dar-0880
ENSDARG00000101130.1
A3QJU3
coq8b
3
iEKPD-Dar-0436
ENSDARG00000062561.6
B1H1M5
adck1
4
iEKPD-Dar-0508
ENSDARG00000073923.3
E7FCQ2
adck2
5
iEKPD-Dar-0531
ENSDARG00000075405.5
F1Q5S6
adck5
6
iEKPD-Dar-0227
ENSDARG00000032426.7
E7F0M3
si:dkey-36g24.3