Felis catus      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Fec-0030
ENSFCAG00000001639.4
A0A2I2UZL5
ADCK1
2
iEKPD-Fec-0402
ENSFCAG00000028490.2
M3X3T3
ADCK2
3
iEKPD-Fec-0143
ENSFCAG00000007728.4
M3W889
ADCK5
4
iEKPD-Fec-0303
ENSFCAG00000018144.3
M3WPK5
COQ8B