Macaca fascicularis      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Maf-0309
ENSMFAG00000038490.1
G7PXM3
COQ8B
2
iEKPD-Maf-0109
ENSMFAG00000007386.1
G7P0Y7
EGM_13014
3
iEKPD-Maf-0090
ENSMFAG00000003597.1
G7PB37
EGM_16849
4
iEKPD-Maf-0175
ENSMFAG00000031783.1
G8F6A3
EGM_19434
5
iEKPD-Maf-0452
ENSMFAG00000045043.1
G8F3M4
EGM_20044