Mesocricetus auratus      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Mea-0108
ENSMAUG00000007724.1
A0A1U7QQQ3
Adck1
2
iEKPD-Mea-0016
ENSMAUG00000000751.1
A0A1U7R4L7
Adck2
3
iEKPD-Mea-0316
ENSMAUG00000016955.1
A0A1U7R2K6
Adck3
4
iEKPD-Mea-0416
ENSMAUG00000020579.1
A0A1U7R3C9
Adck4
5
iEKPD-Mea-0202
ENSMAUG00000012114.1
A0A1U7R500
Adck5