Myotis lucifugus      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Myl-0001
ENSMLUG00000000084.2
G1NSH3
ADCK1
2
iEKPD-Myl-0178
ENSMLUG00000007534.2
G1P9H0
ADCK2
3
iEKPD-Myl-0012
ENSMLUG00000000657.2
G1NTT6
ADCK5
4
iEKPD-Myl-0142
ENSMLUG00000006275.2
G1P6N4
COQ8A
5
iEKPD-Myl-0005
ENSMLUG00000000210.2
G1NSS2
COQ8B