※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Nia-0114	A4A49_06642	A0A1J6HX77	A4A49_06642
2		iEKPD-Nia-0162	A4A49_10128	A0A1J6J7I2	A4A49_10128
3		iEKPD-Nia-0270	A4A49_20336	A0A1J6IVA3	A4A49_20336
4		iEKPD-Nia-0295	A4A49_22032	A0A1J6I4U6	A4A49_22032
5		iEKPD-Nia-0346	A4A49_25185	A0A1J6KDS7	A4A49_25185
6		iEKPD-Nia-0379	A4A49_26992	A0A1J6KB16	A4A49_26992
7		iEKPD-Nia-0467	A4A49_32786	A0A1J6JVG9	A4A49_32786
8		iEKPD-Nia-0471	A4A49_32867	A0A1J6KMQ5	A4A49_32867
9		iEKPD-Nia-0542	A4A49_36733	A0A1J6K6T9	A4A49_36733
10		iEKPD-Nia-g025	A4A49_36735	A0A1J6KFS5	A4A49_36735
11		iEKPD-Nia-0562	A4A49_37525	A0A1J6JAS6	A4A49_37525
12		iEKPD-Nia-g018	A4A49_58400	A0A1J6K9Q0	A4A49_58400
13		iEKPD-Nia-0662	A4A49_60164	A0A1J6IJ19	A4A49_60164