Oreochromis niloticus      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Orn-0330
ENSONIG00000011041.1
I3JYE6
adck1
2
iEKPD-Orn-0241
ENSONIG00000008815.1
I3JQE1
adck2
3
iEKPD-Orn-0204
ENSONIG00000007683.1
I3JLE0
adck5
4
iEKPD-Orn-0012
ENSONIG00000000575.1
I3IVU0
COQ8A
5
iEKPD-Orn-0015
ENSONIG00000000696.1
I3IW88
coq8a
6
iEKPD-Orn-0494
ENSONIG00000016647.1
I3KIM6
LOC100693708