Oryzias latipes      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ore-0073
ENSORLG00000002597.1
H2LBG5
2
iEKPD-Ore-0243
ENSORLG00000008795.1
H2LY30
3
iEKPD-Ore-0491
ENSORLG00000017137.1
H2MRR3
4
iEKPD-Ore-0304
ENSORLG00000010777.1
H2M4Z2
adck1
5
iEKPD-Ore-0385
ENSORLG00000013555.1
H2MEI8
adck5
6
iEKPD-Ore-0546
ENSORLG00000019784.1
H2MZR3
COQ8A