Papio anubis      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Paa-0097
ENSPANG00000007672.2
A0A096NSA6
ADCK1
2
iEKPD-Paa-0101
ENSPANG00000007837.2
A0A096N2B4
ADCK2
3
iEKPD-Paa-0010
ENSPANG00000000709.2
A0A096ND93
ADCK5
4
iEKPD-Paa-0070
ENSPANG00000005934.2
A0A096MYD8
COQ8A
5
iEKPD-Paa-0077
ENSPANG00000006681.3
A0A0A0MVT6
COQ8B