Poecilia formosa      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pof-0045
ENSPFOG00000001709.2
2
iEKPD-Pof-0052
ENSPFOG00000001942.2
A0A087X806
3
iEKPD-Pof-0181
ENSPFOG00000006651.1
A0A087XLL0
4
iEKPD-Pof-0278
ENSPFOG00000009638.2
A0A087XVK2
5
iEKPD-Pof-0311
ENSPFOG00000010994.2
A0A087XZG2
6
iEKPD-Pof-0332
ENSPFOG00000011579.2
A0A087Y0V5
7
iEKPD-Pof-0360
ENSPFOG00000012751.1
A0A087Y494
8
iEKPD-Pof-0456
ENSPFOG00000015960.2
A0A087YDL9