※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074

  Reviewed (0)  or Unreviewed (17) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Prp-0003	PRUPE_1G002700	M5XKN1	PRUPE_1G002700
2		iEKPD-Prp-0132	PRUPE_1G398500	A0A251RD36	PRUPE_1G398500
3		iEKPD-Prp-0162	PRUPE_1G455100	M5XKE4	PRUPE_1G455100
4		iEKPD-Prp-0166	PRUPE_1G461300	M5XY47	PRUPE_1G461300
5		iEKPD-Prp-0316	PRUPE_2G249400	A0A251QLA7	PRUPE_2G249400
6		iEKPD-Prp-0323	PRUPE_2G265700	M5X252	PRUPE_2G265700
7		iEKPD-Prp-0348	PRUPE_3G001200	M5X9X0	PRUPE_3G001200
8		iEKPD-Prp-0353	PRUPE_3G015600	A0A251PTP3	PRUPE_3G015600
9		iEKPD-Prp-0472	PRUPE_3G196900	M5WX24	PRUPE_3G196900
10		iEKPD-Prp-0562	PRUPE_4G034900	M5X2V1	PRUPE_4G034900
11		iEKPD-Prp-0674	PRUPE_4G192100	A0A251PN28	PRUPE_4G192100
12		iEKPD-Prp-0717	PRUPE_5G000100	M5WCN8	PRUPE_5G000100
13		iEKPD-Prp-g030	PRUPE_5G155100	A0A251PCF2	PRUPE_5G155100
14		iEKPD-Prp-0763	PRUPE_5G156400	A0A251P8Z6	PRUPE_5G156400
15		iEKPD-Prp-0893	PRUPE_6G175300	M5W7H4	PRUPE_6G175300
16		iEKPD-Prp-1107	PRUPE_8G046100	A0A251MVL3	PRUPE_8G046100
17		iEKPD-Prp-1128	PRUPE_8G142600	M5W265	PRUPE_8G142600