※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sus-0036	ENSSSCG00000002408.3	A0A287A8L4	ADCK1
2		iEKPD-Sus-0286	ENSSSCG00000016496.3	F1SRP9	ADCK2
3		iEKPD-Sus-0090	ENSSSCG00000005907.4	F1RSN7	ADCK5
4		iEKPD-Sus-0179	ENSSSCG00000010861.3	A0A286ZK64	COQ8A
5		iEKPD-Sus-0362	ENSSSCG00000026331.2	I3LIP8	COQ8B