Takifugu rubripes      Atypical/ABC1


※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Tar-0047
ENSTRUG00000001653.1
H2RUI6
2
iEKPD-Tar-0208
ENSTRUG00000006469.1
H2STU3
3
iEKPD-Tar-0533
ENSTRUG00000016512.1
H2UZ13
4
iEKPD-Tar-0020
ENSTRUG00000000665.1
H2RN81
adck1
5
iEKPD-Tar-0427
ENSTRUG00000013058.1
H2U866
adck5
6
iEKPD-Tar-0462
ENSTRUG00000014182.1
H2UH43
LOC101067122