Felis catus Atypical/FAST
※ FAST family introduction FAST (Fas-activated Serine/Threonine) kinase can catalyze the phosphate group transfer from ATP to Fas-activated Serine/Threonine protein. TIA1 is substrate of FAST kinase, and the phosphorylation will lead to inclusion of FAS exon6, which will produce an mRNA encoding a pro-apoptotic form of teh receptor (1). Since the overall sequence of FAST shares no similarity with ePK, FAST is classified into "Atypical Protein Kinase" group (2). Reference
1. UniProt Annotation: FASTK_HUMAN
2. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
There are 2 genes. Reviewed (0)
or Unreviewed (2) 
※ FAST family introduction FAST (Fas-activated Serine/Threonine) kinase can catalyze the phosphate group transfer from ATP to Fas-activated Serine/Threonine protein. TIA1 is substrate of FAST kinase, and the phosphorylation will lead to inclusion of FAS exon6, which will produce an mRNA encoding a pro-apoptotic form of teh receptor (1). Since the overall sequence of FAST shares no similarity with ePK, FAST is classified into "Atypical Protein Kinase" group (2). Reference
1. UniProt Annotation: FASTK_HUMAN
2. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
There are 2 genes. Reviewed (0)
or Unreviewed (2) | No. | Status | iEKPD ID | Ensemble Gene ID | UniProt Accession | Gene Name |
|---|---|---|---|---|---|
| 1 | | ||||
| 2 | |