Felis catus      Atypical/TIF1


※ TIF1 family introduction

    TIF1, Transcriptional Intermediary Factor 1, contains three members in human genome, TIF1a, TIF1b and TIF1g, and belong to atypical protein kinase group (1). The autophosphorylation activity of TIF1a has been detected in immunopurified, bacculovirus-produced protein. TIFs participate in transcriptional machinery and may mediate the phosphorylation of several TATA-associated factors. Bromodomains are also found in TIFs, which are present in BRD kinase family, which suggest that bromodomain is associated with kinase activity (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikipedia annotation: TIF1.


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Fec-0476
ENSFCAG00000038306.1
A0A2I2UI40
2
iEKPD-Fec-0469
ENSFCAG00000004091.4
M3W1J7
TRIM24
3
iEKPD-Fec-0468
ENSFCAG00000003755.3
M3W0W7
TRIM28