Papio anubis      Atypical/TIF1


※ TIF1 family introduction

    TIF1, Transcriptional Intermediary Factor 1, contains three members in human genome, TIF1a, TIF1b and TIF1g, and belong to atypical protein kinase group (1). The autophosphorylation activity of TIF1a has been detected in immunopurified, bacculovirus-produced protein. TIFs participate in transcriptional machinery and may mediate the phosphorylation of several TATA-associated factors. Bromodomains are also found in TIFs, which are present in BRD kinase family, which suggest that bromodomain is associated with kinase activity (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikipedia annotation: TIF1.


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Paa-0486
ENSPANG00000007105.2
A0A096NFE9
TRIM24
2
iEKPD-Paa-0488
ENSPANG00000014391.2
A0A2I3MME8
TRIM28
3
iEKPD-Paa-0490
ENSPANG00000016076.2
A0A2I3MNS3
TRIM33