Tupaia belangeri      Atypical/TIF1


※ TIF1 family introduction

    TIF1, Transcriptional Intermediary Factor 1, contains three members in human genome, TIF1a, TIF1b and TIF1g, and belong to atypical protein kinase group (1). The autophosphorylation activity of TIF1a has been detected in immunopurified, bacculovirus-produced protein. TIFs participate in transcriptional machinery and may mediate the phosphorylation of several TATA-associated factors. Bromodomains are also found in TIFs, which are present in BRD kinase family, which suggest that bromodomain is associated with kinase activity (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikipedia annotation: TIF1.


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Tub-0405
ENSTBEG00000001926.1
A0A077B6X9
2
iEKPD-Tub-0414
ENSTBEG00000017201.1
3
iEKPD-Tub-0406
ENSTBEG00000005885.1