Cavia porcellus      CAMK/DAPK


※ DAPK family introduction

    DAPK (Death-associated protein kinase) belongs to the CAMK group. DAPK contains DAPK1, DAPK, Zipper interacting kinase (ZIPK, also named DAPK-3), DAP kinase related apoptosis inducing protein kinase DRAK1 and DRAK2. They share a highly conserved catalytic domain and diverse extracatalytic domains which are associated with different functions. DAPK proteins can activate a variety of downstream cell signaling pathway and then induce cell death via p53 or p53-independent apoptosis or autophagy. In addition, death signal can also stimuli the DAPK cascade signaling pathway and finally induce cell death (1).

Reference
1. Lin, Y., Hupp, T.R. and Stevens, C. (2010) Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death. FEBS J, 277, 48-57. PMID: 19878313


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cap-0031
ENSCPOG00000000987.4
H0UV62
DAPK1
2
iEKPD-Cap-0024
ENSCPOG00000000890.4
A0A286X7D6
Dapk2
3
iEKPD-Cap-0436
ENSCPOG00000031679.1
A0A286XZK0
Dapk3
4
iEKPD-Cap-0287
ENSCPOG00000012689.4
H0VM01
STK17A
5
iEKPD-Cap-0435
ENSCPOG00000031678.1
A0A286XP92
STK17B