Danio rerio      CAMK/DAPK


※ DAPK family introduction

    DAPK (Death-associated protein kinase) belongs to the CAMK group. DAPK contains DAPK1, DAPK, Zipper interacting kinase (ZIPK, also named DAPK-3), DAP kinase related apoptosis inducing protein kinase DRAK1 and DRAK2. They share a highly conserved catalytic domain and diverse extracatalytic domains which are associated with different functions. DAPK proteins can activate a variety of downstream cell signaling pathway and then induce cell death via p53 or p53-independent apoptosis or autophagy. In addition, death signal can also stimuli the DAPK cascade signaling pathway and finally induce cell death (1).

Reference
1. Lin, Y., Hupp, T.R. and Stevens, C. (2010) Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death. FEBS J, 277, 48-57. PMID: 19878313


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dar-0408
ENSDARG00000060093.6
A5WVL9
dapk1
2
iEKPD-Dar-0423
ENSDARG00000061096.7
E7F1A1
dapk2a
3
iEKPD-Dar-0927
ENSDARG00000103666.2
A0A0R4IK49
dapk2b
4
iEKPD-Dar-0514
ENSDARG00000074447.4
E9QHI3
dapk3
5
iEKPD-Dar-0239
ENSDARG00000034210.10
F1QN42
si:dkey-240h12.4
6
iEKPD-Dar-0518
ENSDARG00000074715.4
F1R026
stk17a
7
iEKPD-Dar-0111
ENSDARG00000015922.9
A0JML4
stk17al
8
iEKPD-Dar-0103
ENSDARG00000014348.6
Q6PHV6
stk17b