Oreochromis niloticus      CAMK/DCAMKL


※ DCAMKL family introduction

    DCAMKL, Doublecortin-like and CAM kinase-like protein, belong to CAMKL group. Three members have been found in human, DCAMKL1-3. DCAMKL1 may participate in calcium-signaling pathway and control the neuronal migration in the developing brain (1). DCAML2 has little Ca(2+)/CAM affinity compared with other CAMK proteins and may be involved in down regulation of CRE-dependent gene activation via phosphorylating CREB coactivator CRT/TORC2 (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation: DCLK1_HUMAN
3. UniProt Annotation: DCLK2_HUMAN


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Orn-0150
ENSONIG00000005549.1
I3JDN5
DCLK1 (1 of many)
2
iEKPD-Orn-0284
ENSONIG00000010034.1
I3JUS5
DCLK2
3
iEKPD-Orn-0209
ENSONIG00000007802.1
I3JLT3
LOC100704388
4
iEKPD-Orn-0389
ENSONIG00000012617.1
I3K435
LOC100704838