Oryzias latipes      CAMK/DCAMKL


※ DCAMKL family introduction

    DCAMKL, Doublecortin-like and CAM kinase-like protein, belong to CAMKL group. Three members have been found in human, DCAMKL1-3. DCAMKL1 may participate in calcium-signaling pathway and control the neuronal migration in the developing brain (1). DCAML2 has little Ca(2+)/CAM affinity compared with other CAMK proteins and may be involved in down regulation of CRE-dependent gene activation via phosphorylating CREB coactivator CRT/TORC2 (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation: DCLK1_HUMAN
3. UniProt Annotation: DCLK2_HUMAN


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ore-0087
ENSORLG00000003086.1
H2LD50
2
iEKPD-Ore-0322
ENSORLG00000011581.1
H2M7P9
3
iEKPD-Ore-0106
ENSORLG00000003672.1
H2LF46
DCLK1 (1 of many)
4
iEKPD-Ore-0207
ENSORLG00000007601.1
H2LTW5
DCLK2
5
iEKPD-Ore-0110
ENSORLG00000003926.1
H2LG10
LOC101167140