Tetraodon nigroviridis      CAMK/DCAMKL


※ DCAMKL family introduction

    DCAMKL, Doublecortin-like and CAM kinase-like protein, belong to CAMKL group. Three members have been found in human, DCAMKL1-3. DCAMKL1 may participate in calcium-signaling pathway and control the neuronal migration in the developing brain (1). DCAML2 has little Ca(2+)/CAM affinity compared with other CAMK proteins and may be involved in down regulation of CRE-dependent gene activation via phosphorylating CREB coactivator CRT/TORC2 (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation: DCLK1_HUMAN
3. UniProt Annotation: DCLK2_HUMAN


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ten-0297
ENSTNIG00000009924.1
H3CX31
2
iEKPD-Ten-0334
ENSTNIG00000011249.1
H3D102
3
iEKPD-Ten-0537
ENSTNIG00000016978.1
H3DHV7
4
iEKPD-Ten-0508
ENSTNIG00000016267.1
H3DFR7
DCLK1 (1 of many)
5
iEKPD-Ten-0559
ENSTNIG00000017733.1
H3DK37
DCLK2 (1 of many)