Zymoseptoria tritici      CDC25/CDC25


※ CDC25 family introduction

    CDC25 phosphatase contains three members in human genome, which are known as, cdc25A, cdc25B and cdc25C. CDC25 phosphatase is distantly related to other members of the PTP superfamily and rhodanese domain contribute to its catalytic activity (1). CDC25s are key regulator of cell cycle. Through dephosphorylation Thr14 and Tyr15 in cyclin-dependent kinases, CDK is activated and in turn drives the progression through the cell cycle (2).

Reference
1. Wang, W.Q., Sun, J.P. and Zhang, Z.Y. (2003) An overview of the protein tyrosine phosphatase superfamily. Curr Top Med Chem, 3, 739-748. PMID: 12678841
2. Karlsson-Rosenthal, C. and Millar, J.B. (2006) Cdc25: mechanisms of checkpoint inhibition and recovery. Trends Cell Biol, 16, 285-292. PMID: 16682204


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Zyt-0175
Mycgr3G59682
F9XCQ7
MgCDC25
2
iEKPD-Zyt-g002
Mycgr3G28957
F9XCG8
MYCGRDRAFT_28957
3
iEKPD-Zyt-g010
Mycgr3G75985
F9XKL8
MYCGRDRAFT_75985
4
iEKPD-Zyt-g014
Mycgr3G93513
F9XCF3
MYCGRDRAFT_93513