※ CK1 family introduction

    CK1 (Casein kinase I) is characterized by its Ser/Thr protein kinase catalytic activity on phoshorylation of casein in vitro in a cycle AMP-independent manner. Six isoforms and CK1-like kinase have been identified in this family. Sequence analysis shows that all members share a N-terminal conserved kinase catalytic domain and a variable C-terminal sequence. Several potential regulatory mechanisms for CK1s have been described including activation via phosphorylation of PKA, 14-3-3 binding and autoinhibition. CK1s are involved in a variety of cellular processes via phosphorylation of a large range of substrates, for instance, stabilizing AIB1 and increasing Erα transcriptional activity, facilitating CK1α/FADD/CaM complex assembly for proper cell cycle progression, reducing DNA-binding activity of Dnmt1, blocking nuclear export and so on. (1)

Reference
1. Cheong, J.K. and Virshup, D.M. (2011) Casein kinase 1: Complexity in the family. Int J Biochem Cell Biol, 43, 465-469. PMID: 21145983

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Glm-0263	GLYMA_03G101400
2		iEKPD-Glm-0664	GLYMA_07G0076001
3		iEKPD-Glm-0665	GLYMA_07G0076002
4		iEKPD-Glm-0862	GLYMA_08G190300
5		iEKPD-Glm-1782	GLYMA_15G1711001
6		iEKPD-Glm-1783	GLYMA_15G1711002
7		iEKPD-Glm-1784	GLYMA_15G171500
8		iEKPD-Glm-1990	GLYMA_17G195900
9		iEKPD-Glm-1581	GLYMA_13G348100	A0A0R4J4Y0	100778165
10		iEKPD-Glm-0350	GLYMA_04G085900	I1JUX1	100778855
11		iEKPD-Glm-0351	GLYMA_04G086000	I1JUX3	100779382
12		iEKPD-Glm-0512	GLYMA_05G228700	I1K5X5	100779936
13		iEKPD-Glm-0284	GLYMA_03G164700	I1JP51	100781494
14		iEKPD-Glm-1080	GLYMA_10G038600	I1L8F7	100783824
15		iEKPD-Glm-1465	GLYMA_13G105900	A0A0R0GL93	100785851
16		iEKPD-Glm-0975	GLYMA_09G065200	I1L1K3	100786777
17		iEKPD-Glm-1473	GLYMA_13G125000	I1LYM5	100789031
18		iEKPD-Glm-1135	GLYMA_10G181700	I1LC61	100790721
19		iEKPD-Glm-0544	GLYMA_06G084300	I1K9C5	100792736
20		iEKPD-Glm-1720	GLYMA_15G025900	K7M967	100795570
21		iEKPD-Glm-0874	GLYMA_08G201600	I1KV29	100799630
22		iEKPD-Glm-0546	GLYMA_06G087500	I1K9F9	100800125
23		iEKPD-Glm-0787	GLYMA_08G035700	I1KPY8	100800342
24		iEKPD-Glm-0671	GLYMA_07G016100	I1KGJ5	100800869
25		iEKPD-Glm-1847	GLYMA_16G041500	I1ML29	100801967
26		iEKPD-Glm-0946	GLYMA_08G361700	I1KZH6	100803733
27		iEKPD-Glm-1029	GLYMA_09G193600	I1L4L3	100805890
28		iEKPD-Glm-2365	GLYMA_20G244000	I1NJ88	100807373
29		iEKPD-Glm-2228	GLYMA_19G166100	I1N9S4	100807882
30		iEKPD-Glm-0348	GLYMA_04G082900	I1JUU5	100810377
31		iEKPD-Glm-1933	GLYMA_17G053500	I1MSF4	100811567
32		iEKPD-Glm-2174	GLYMA_18G300100	I1N5F2	100819969