※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Gor-0237	B456_002G218100	A0A0D2RAI9	B456_002G218100
2		iEKPD-Gor-0339	B456_004G042400	A0A0D2P6K1	B456_004G042400
3		iEKPD-Gor-0360	B456_004G156700	A0A0D2R5E7	B456_004G156700
4		iEKPD-Gor-0589	B456_006G089300	A0A0D2SUB7	B456_006G089300
5		iEKPD-Gor-0590	B456_006G089400	A0A0D2NP21	B456_006G089400
6		iEKPD-Gor-0707	B456_007G096100	A0A0D2SAC4	B456_007G096100
7		iEKPD-Gor-0808	B456_007G308500	A0A0D2STU8	B456_007G308500
8		iEKPD-Gor-0863	B456_008G045800	A0A0D2T0B2	B456_008G045800
9		iEKPD-Gor-0896	B456_008G136600	A0A0D2U2P4	B456_008G136600
10		iEKPD-Gor-1293	B456_010G241600	A0A0D2SYA0	B456_010G241600