※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Hea-2030	HannXRQ_Chr14g0450461	A0A251SJ73	ATSK11
2		iEKPD-Hea-0813	HannXRQ_Chr07g0198881	A0A251UCZ2	ATSK13
3		iEKPD-Hea-1868	HannXRQ_Chr13g0426211	A0A251SXQ5	ATSK32
4		iEKPD-Hea-0265	HannXRQ_Chr03g0067951	A0A251V653	ATSK41
5		iEKPD-Hea-1450	HannXRQ_Chr11g0341851	A0A251TC11	BIN2
6		iEKPD-Hea-0498	HannXRQ_Chr04g0115771	A0A251V155	GSK1
7		iEKPD-Hea-0520	HannXRQ_Chr04g0121911	A0A251V1B6	HannXRQ_Chr04g0121911
8		iEKPD-Hea-0698	HannXRQ_Chr06g0169741	A0A251UHD9	HannXRQ_Chr06g0169741
9		iEKPD-Hea-2180	HannXRQ_Chr15g0480751	A0A251S8Z7	HannXRQ_Chr15g0480751
10		iEKPD-Hea-2459	HannXRQ_Chr17g0555471	A0A251RSM3	HannXRQ_Chr17g0555471
11		iEKPD-Hea-1111	HannXRQ_Chr09g0266281	A0A251TYV3	MSK1
12		iEKPD-Hea-1223	HannXRQ_Chr10g0299521	A0A251TL84	MSK2
13		iEKPD-Hea-0696	HannXRQ_Chr06g0168041	A0A251UGF7	MSK3