※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mae-0087	MANES_01G232500	A0A2C9WPX0	MANES_01G232500
2		iEKPD-Mae-0100	MANES_01G261000	A0A2C9WPA4	MANES_01G261000
3		iEKPD-Mae-0132	MANES_02G088500	A0A2C9WET6	MANES_02G088500
4		iEKPD-Mae-0398	MANES_05G011400	A0A2C9VSB4	MANES_05G011400
5		iEKPD-Mae-0409	MANES_05G039100	A0A2C9VV97	MANES_05G039100
6		iEKPD-Mae-0577	MANES_07G025500	A0A251KFQ7	MANES_07G025500
7		iEKPD-Mae-0685	MANES_08G108500	A0A251KCJ4	MANES_08G108500
8		iEKPD-Mae-0783	MANES_09G180000	A0A251KPQ9	MANES_09G180000
9		iEKPD-Mae-0860	MANES_10G116600	A0A2C9V5E7	MANES_10G116600
10		iEKPD-Mae-1387	MANES_17G057800	A0A2C9U708	MANES_17G057800