※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Met-0432	MTR_2g083940	G7IM77	11406396
2		iEKPD-Met-0214	MTR_1g084760	G7IAA8	11406490
3		iEKPD-Met-0218	MTR_1g086370	G7IBT9	11417436
4		iEKPD-Met-1294	MTR_7g076030	G7L1H1	11423486
5		iEKPD-Met-0298	MTR_2g005620	Q1SL21	11430329
6		iEKPD-Met-1362	MTR_7g110060	G7KTQ8	11431576
7		iEKPD-Met-0334	MTR_2g016490	I3SJN2	25485989
8		iEKPD-Met-1576	MTR_8g432510	A0A072TP39	25502314