※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Orh-0055	OBART01G09540	A0A0D3ELT8
2		iEKPD-Orh-0183	OBART01G45990	A0A0D3EZE5
3		iEKPD-Orh-0238	OBART02G10020	A0A0D3F2W6
4		iEKPD-Orh-0459	OBART03G40490	A0A0D3FR76
5		iEKPD-Orh-0611	OBART05G02350	A0A0D3G2X3
6		iEKPD-Orh-1154	OBART10G16100	A0A0D3HFR6
7		iEKPD-Orh-0627	OBART05G06820	A0A0D3G4D7	4338079
8		iEKPD-Orh-0763	OBART06G17890	A0A0D3GHM3	4341251