※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Orm-0039	OMERI01G06780	A0A0E0BYU0
2		iEKPD-Orm-0054	OMERI01G09550	A0A0E0C009
3		iEKPD-Orm-0438	OMERI03G37310	A0A0E0D9D7
4		iEKPD-Orm-0572	OMERI05G02470	A0A0E0DLN7
5		iEKPD-Orm-1019	OMERI10G12700	A0A0E0F024
6		iEKPD-Orm-0580	OMERI05G06080	A0A0E0DN84	4338079
7		iEKPD-Orm-0699	OMERI06G18520	A0A0E0E2R2	4341251