※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Orv-0062	ONIVA01G08930	A0A0E0FIB0
2		iEKPD-Orv-0078	ONIVA01G11990	A0A0E0FJG5
3		iEKPD-Orv-0265	ONIVA02G11130	A0A0E0G432
4		iEKPD-Orv-0518	ONIVA03G42370	A0A0E0GW90
5		iEKPD-Orv-0666	ONIVA05G02250	A0A0E0H913
6		iEKPD-Orv-0680	ONIVA05G07620	A0A0E0HAZ9
7		iEKPD-Orv-1232	ONIVA10G17660	A0A0E0IV64
8		iEKPD-Orv-0826	ONIVA06G21300	A0A0E0HS67	4341251