※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Orr-0048	ORUFI01G07330	A0A0E0MSV9
2		iEKPD-Orr-0061	ORUFI01G10400	A0A0E0MU02
3		iEKPD-Orr-0252	ORUFI02G10080	A0A0E0NC80
4		iEKPD-Orr-0476	ORUFI03G42230	A0A0E0P3Q6
5		iEKPD-Orr-0638	ORUFI05G02470	A0A0E0PH59
6		iEKPD-Orr-1199	ORUFI10G17170	A0A0E0R1I2
7		iEKPD-Orr-0652	ORUFI05G07330	A0A0E0PIV0	4338079
8		iEKPD-Orr-0791	ORUFI06G18940	A0A0E0PYY4	4341251