※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Phv-0236	PHAVU_002G239600g	V7CMM7	PHAVU_002G239600g
2		iEKPD-Phv-0511	PHAVU_005G094100g	V7BYP5	PHAVU_005G094100g
3		iEKPD-Phv-0645	PHAVU_006G1745000g	V7BPX2	PHAVU_006G1745000g
4		iEKPD-Phv-0675	PHAVU_006G219700g	V7BU40	PHAVU_006G219700g
5		iEKPD-Phv-0775	PHAVU_007G204000g	V7BHM7	PHAVU_007G204000g
6		iEKPD-Phv-0864	PHAVU_008G072800g	V7B2Z7	PHAVU_008G072800g
7		iEKPD-Phv-0913	PHAVU_008G156000g	V7B569	PHAVU_008G156000g
8		iEKPD-Phv-1016	PHAVU_009G089900g	V7ATI9	PHAVU_009G089900g
9		iEKPD-Phv-1132	PHAVU_010G090200g	V7AN42	PHAVU_010G090200g
10		iEKPD-Phv-1205	PHAVU_011G128000g	V7AIY8	PHAVU_011G128000g