※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Php-0444	PP1S306_43V6	A9TSH9	PHYPADRAFT_197781
2		iEKPD-Php-0445	PP1S306_62V6	A9TSI8	PHYPADRAFT_197793
3		iEKPD-Php-0554	PP1S391_47V6	A9TZV6	PHYPADRAFT_61509
4		iEKPD-Php-0734	PP1S74_168V6	A9SFW7	PHYPA_004261
5		iEKPD-Php-0689	PP1S60_85V6	A9SAB0	PHYPA_006640
6		iEKPD-Php-0649	PP1S52_55V6	A9S6L2	PHYPA_017155
7		iEKPD-Php-0686	PP1S60_100V6	Q6VM14	SK1