※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Pot-0498	POPTR_0004s23420
2		iEKPD-Pot-0243	POPTR_0002s15640	B9GPW2	POPTR_0002s15640g
3		iEKPD-Pot-0257	POPTR_0002s19110	B9GSY1	POPTR_0002s19110g
4		iEKPD-Pot-0412	POPTR_0004s05770	B9H2G5	POPTR_0004s05770g
5		iEKPD-Pot-0512	POPTR_0005s00710	B9N435	POPTR_0005s00710g
6		iEKPD-Pot-1123	POPTR_0011s07130	B9I1J2	POPTR_0011s07130g
7		iEKPD-Pot-1254	POPTR_0013s00610	B9I6N0	POPTR_0013s00610g
8		iEKPD-Pot-1330	POPTR_0014s07120	B9IC54	POPTR_0014s07120g
9		iEKPD-Pot-1752	POPTR_0022s00490	U7E1J6	POPTR_0022s00490g